Cargando…

Alterations in Red Blood Cell Functionality Induced by an Indole Scaffold Containing a Y-Iminodiketo Moiety: Potential Antiproliferative Conditions

We have recently proposed a new erythrocyte-based model of study to predict the antiproliferative effects of selected heterocyclic scaffolds. Starting from the metabolic similarity between erythrocytes and cancer cells, we have demonstrated how the metabolic derangement induced by an indolone-based...

Descripción completa

Detalles Bibliográficos
Autores principales:	Scala, Angela, Ficarra, Silvana, Russo, Annamaria, Barreca, Davide, Giunta, Elena, Galtieri, Antonio, Grassi, Giovanni, Tellone, Ester
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019890/ https://www.ncbi.nlm.nih.gov/pubmed/27651854 http://dx.doi.org/10.1155/2016/2104247

Ejemplares similares

Short-Term Effects of Chlorpromazine on Oxidative Stress in Erythrocyte Functionality: Activation of Metabolism and Membrane Perturbation
por: Ficarra, Silvana, et al.
Publicado: (2016)

Implication of COVID-19 on Erythrocytes Functionality: Red Blood Cell Biochemical Implications and Morpho-Functional Aspects
por: Russo, Annamaria, et al.
Publicado: (2022)

How does resveratrol influence the genesis of some neurodegenerative diseases?
por: Tellone, Ester, et al.
Publicado: (2016)

Resveratrol: A Focus on Several Neurodegenerative Diseases
por: Tellone, Ester, et al.
Publicado: (2015)

NO Metabolites Levels in Human Red Blood Cells are Affected by Palytoxin, an Inhibitor of Na(+)/K(+)-ATPase Pump
por: Carelli-Alinovi, Cristiana, et al.
Publicado: (2014)

The Neuroprotective Potentiality of Flavonoids on Alzheimer’s Disease
por: Calderaro, Antonella, et al.
Publicado: (2022)

Catechins and Proanthocyanidins Involvement in Metabolic Syndrome
por: Patanè, Giuseppe Tancredi, et al.
Publicado: (2023)

Biotechnological Applications and Health-Promoting Properties of Flavonols: An Updated View
por: Gervasi, Teresa, et al.
Publicado: (2022)

Antiproliferative Effect of Indole Phytoalexins
por: Chripkova, Martina, et al.
Publicado: (2016)

Synthesis and Evaluation of Novel α-Aminoamides Containing an Indole Moiety for the Treatment of Neuropathic Pain
por: Li, Haotian, et al.
Publicado: (2016)

Base-Free Synthesis and Photophysical Properties of New Schiff Bases Containing Indole Moiety
por: Soliman, Ahmed I. A., et al.
Publicado: (2022)

Synthesis of indole derivatives as prevalent moieties present in selected alkaloids
por: Heravi, Majid M., et al.
Publicado: (2021)

Synthesis of Aryl Propionamide Scaffold Containing a Pentafluorosulfanyl Moiety as SARMs
por: Shao, Pingxuan, et al.
Publicado: (2019)

Synthesis, Molecular Docking Analysis and in Vitro Biological Evaluation of Some New Heterocyclic Scaffolds-Based Indole Moiety as Possible Antimicrobial Agents
por: Hassan, Entesar A., et al.
Publicado: (2022)

Synthesis and Antiproliferative Activity of Novel Heterocyclic Indole-Trimethoxyphenyl Conjugates
por: Cahill, Michael M., et al.
Publicado: (2017)

Late‐Stage Chemoenzymatic Installation of Hydroxy‐Bearing Allyl Moiety on the Indole Ring of Tryptophan‐Containing Peptides
por: Mupparapu, Nagaraju, et al.
Publicado: (2022)

Design, Synthesis, and In Vitro Antiproliferative Activity of Hydantoin and Purine Derivatives with the 4-Acetylphenylpiperazinylalkyl Moiety
por: Zagórska, Agnieszka, et al.
Publicado: (2021)

Synthesis of adenosine analogues with indole moiety as human adenosine A(3) receptor ligands
por: Xia, Yan, et al.
Publicado: (2018)

Solid-State Luminescent Materials Containing Both Indole and Pyrimidine Moieties: Design, Synthesis, and Density Functional Theory Calculations
por: Younis, Osama, et al.
Publicado: (2022)

Synthesis and Antiproliferative Activity against Cancer Cells of Indole-Aryl-Amide Derivatives
por: Zhao, Junwei, et al.
Publicado: (2022)

Design, Synthesis, and Evaluation of Novel Indole Hybrid Chalcones and Their Antiproliferative and Antioxidant Activity
por: Kudličková, Zuzana, et al.
Publicado: (2023)

Quinoxaline Moiety: A Potential Scaffold against Mycobacterium tuberculosis
por: Montana, Marc, et al.
Publicado: (2021)

Synthesis and Antiproliferative Evaluation of Novel Hybrids of Dehydroabietic Acid Bearing 1,2,3-Triazole Moiety
por: Li, Fang-Yao, et al.
Publicado: (2019)

Benzimidazole scaffolds as promising antiproliferative agents: a review
por: Tahlan, Sumit, et al.
Publicado: (2019)

Indole: The After Next Scaffold of Antiplasmodial Agents?
por: Surur, Abdrrahman Shemsu, et al.
Publicado: (2020)

Indole-Based Hydrazones Containing A Sulfonamide Moiety as Selective Inhibitors of Tumor-Associated Human Carbonic Anhydrase Isoforms IX and XII
por: Demir-Yazıcı, Kübra, et al.
Publicado: (2019)

5,8-Quinolinedione Scaffold as a Promising Moiety of Bioactive Agents
por: Kadela-Tomanek, Monika, et al.
Publicado: (2019)

Pyridine Scaffolds, Phenols and Derivatives of Azo Moiety: Current Therapeutic Perspectives
por: Tahir, Tehreem, et al.
Publicado: (2021)

Synthesis and Antiproliferative Evaluation of Novel Longifolene-Derived Tetralone Derivatives Bearing 1,2,4-Triazole Moiety
por: Zhu, Xia-Ping, et al.
Publicado: (2020)

Antiproliferative Aspidosperma-Type Monoterpenoid Indole Alkaloids from Bousigonia mekongensis Inhibit Tubulin Polymerization
por: Zhang, Yu, et al.
Publicado: (2019)

New Isatin–Indole Conjugates: Synthesis, Characterization, and a Plausible Mechanism of Their in vitro Antiproliferative Activity
por: Al-Wabli, Reem I, et al.
Publicado: (2020)

Design, Synthesis and Antiproliferative Evaluation of Bis-Indole Derivatives with a Phenyl Linker: Focus on Autophagy
por: Marianna, Budovska, et al.
Publicado: (2022)

Design, Synthesis, and Biological Evaluation of Indole-2-carboxamides as Potential Multi-Target Antiproliferative Agents
por: Al-Wahaibi, Lamya H., et al.
Publicado: (2023)

Indol-3-ylglyoxylamide as Privileged Scaffold in Medicinal Chemistry
por: Barresi, Elisabetta, et al.
Publicado: (2023)

Melatonin Analogue Antiproliferative and Cytotoxic Effects on Human Prostate Cancer Cells
por: Calastretti, Angela, et al.
Publicado: (2018)

Synthesis, Characterization, Antimicrobial, DNA Cleavage, and Antioxidant Studies of Some Metal Complexes Derived from Schiff Base Containing Indole and Quinoline Moieties
por: Karekal, Mahendra Raj, et al.
Publicado: (2013)

Pyrrolizine/indolizine-bearing (un)substituted isoindole moiety: design, synthesis, antiproliferative and MDR reversal activities, and in silico studies
por: AbdelSamad, Amr L., et al.
Publicado: (2023)

A magnetic porous organic polymer: catalytic application in the synthesis of hybrid pyridines with indole, triazole and sulfonamide moieties
por: Torabi, Morteza, et al.
Publicado: (2022)

Design, Synthesis, and Antiproliferative Activity of Selective Histone Deacetylases 6 Inhibitors Containing a Tetrahydropyridopyrimidine Scaffold
por: Wang, Bin, et al.
Publicado: (2023)

The In Vitro Potential of 1-(1H-indol-3-yl) Derivatives against Candida spp. and Aspergillus niger as Tyrosinase Inhibitors
por: Gervasi, Teresa, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_l2u0ms6119966v2950qt6qp8fl