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Recent Advances of the NLRP3 Inflammasome in Central Nervous System Disorders

Inflammasomes are multiprotein complexes that trigger the activation of caspases-1 and subsequently the maturation of proinflammatory cytokines interleukin-1β and interleukin-18. These cytokines play a critical role in mediating inflammation and innate immunity response. Among various inflammasome c...

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Detalles Bibliográficos
Autores principales: Zhou, Keren, Shi, Ligen, Wang, Yan, Chen, Sheng, Zhang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019917/
https://www.ncbi.nlm.nih.gov/pubmed/27652274
http://dx.doi.org/10.1155/2016/9238290