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Bioscreening and expression of a camel anti-CTGF VHH nanobody and its renaturation by a novel dialysis–dilution method

The variable regions of the camel heavy chain antibody, also known as nanobody is the smallest antibody with antigen-binding efficiency. CTGF is considered important during extracellular matrix deposition which was involved in the pathogenesis of fibrosis related diseases. There are several anti-CTG...

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Detalles Bibliográficos
Autores principales: Xue, Xiulei, Fan, Xiaobo, Qu, Qingrong, Wu, Guoqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019992/
https://www.ncbi.nlm.nih.gov/pubmed/27620736
http://dx.doi.org/10.1186/s13568-016-0249-1