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Orf Virus 002 Protein Targets Ovine Protein S100A4 and Inhibits NF-κB Signaling

Orf virus (ORFV), a member of Parapoxvirus, has evolved various strategies to modulate the immune responses of host cells. The ORFV-encoded protein ORFV002, a regulator factor, has been found to inhibit the acetylation of NF-κB-p65 by blocking phosphorylation of NF-κB-p65 at Ser(276) and also to dis...

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Detalles Bibliográficos
Autores principales: Chen, Daxiang, Zheng, Zewei, Xiao, Bin, Li, Wei, Long, Mingjian, Chen, Huiqin, Li, Ming, Rock, Daniel L., Hao, Wenbo, Luo, Shuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020088/
https://www.ncbi.nlm.nih.gov/pubmed/27679610
http://dx.doi.org/10.3389/fmicb.2016.01389