A Case for Microtubule Vulnerability in Amyotrophic Lateral Sclerosis: Altered Dynamics During Disease

Amyotrophic lateral sclerosis (ALS) is an aggressive multifactorial disease converging on a common pathology: the degeneration of motor neurons (MNs), their axons and neuromuscular synapses. This vulnerability and dysfunction of MNs highlights the dependency of these large cells on their intracellul...

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Detalles Bibliográficos
Autores principales: Clark, Jayden A., Yeaman, Elise J., Blizzard, Catherine A., Chuckowree, Jyoti A., Dickson, Tracey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020100/
https://www.ncbi.nlm.nih.gov/pubmed/27679561
http://dx.doi.org/10.3389/fncel.2016.00204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020100/
https://www.ncbi.nlm.nih.gov/pubmed/27679561
http://dx.doi.org/10.3389/fncel.2016.00204

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