Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson’s disease model induced by MPTP

Accumulating evidence suggest mitochondria-mediated pathways play an important role in dopaminergic neuronal cell death in Parkinson’s disease (PD). Drp1, a key regulator of mitochondrial fission, has been shown to be activated and translocated to mitochondria under stress, leading to excessive mito...

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Detalles Bibliográficos
Autores principales: Filichia, Emily, Hoffer, Barry, Qi, Xin, Luo, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020318/
https://www.ncbi.nlm.nih.gov/pubmed/27619562
http://dx.doi.org/10.1038/srep32656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020318/
https://www.ncbi.nlm.nih.gov/pubmed/27619562
http://dx.doi.org/10.1038/srep32656

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