The porin VDAC2 is the mitochondrial platform for Bax retrotranslocation

The pro-apoptotic Bcl-2 protein Bax can permeabilize the outer mitochondrial membrane and therefore commit human cells to apoptosis. Bax is regulated by constant translocation to the mitochondria and retrotranslocation back into the cytosol. Bax retrotranslocation depends on pro-survival Bcl-2 prote...

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Detalles Bibliográficos
Autores principales: Lauterwasser, Joachim, Todt, Franziska, Zerbes, Ralf M., Nguyen, Thanh Ngoc, Craigen, William, Lazarou, Michael, van der Laan, Martin, Edlich, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020405/
https://www.ncbi.nlm.nih.gov/pubmed/27620692
http://dx.doi.org/10.1038/srep32994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020405/
https://www.ncbi.nlm.nih.gov/pubmed/27620692
http://dx.doi.org/10.1038/srep32994

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