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Identifying model error in metabolic flux analysis – a generalized least squares approach

BACKGROUND: The estimation of intracellular flux through traditional metabolic flux analysis (MFA) using an overdetermined system of equations is a well established practice in metabolic engineering. Despite the continued evolution of the methodology since its introduction, there has been little foc...

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Detalles Bibliográficos
Autores principales: Sokolenko, Stanislav, Quattrociocchi, Marco, Aucoin, Marc G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020535/
https://www.ncbi.nlm.nih.gov/pubmed/27619919
http://dx.doi.org/10.1186/s12918-016-0335-7