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Identifying model error in metabolic flux analysis – a generalized least squares approach
BACKGROUND: The estimation of intracellular flux through traditional metabolic flux analysis (MFA) using an overdetermined system of equations is a well established practice in metabolic engineering. Despite the continued evolution of the methodology since its introduction, there has been little foc...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020535/ https://www.ncbi.nlm.nih.gov/pubmed/27619919 http://dx.doi.org/10.1186/s12918-016-0335-7 |