Necroptosis Is an Important Severity Determinant and Potential Therapeutic Target in Experimental Severe Pancreatitis

BACKGROUND & AIMS: Severe acute pancreatitis is characterized by acinar cell death and inflammation. Necroptosis is an aggressive and proinflammatory mode of cell death that can be prevented by necrostatin-1 administration or receptor-interacting protein kinase (RIP3) deletion. METHODS: Mouse pa...

Descripción completa

Detalles Bibliográficos
Autores principales: Louhimo, Johanna M., Steer, Michael L., Perides, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020563/
https://www.ncbi.nlm.nih.gov/pubmed/27642624
http://dx.doi.org/10.1016/j.jcmgh.2016.04.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020563/
https://www.ncbi.nlm.nih.gov/pubmed/27642624
http://dx.doi.org/10.1016/j.jcmgh.2016.04.002

Ejemplares similares