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Interaction of uromodulin and complement factor H enhances C3b inactivation

Recent studies suggest that uromodulin plays an important role in chronic kidney diseases. It can interact with several complement components, various cytokines and immune system cells. Complement factor H (CFH), as a regulator of the complement alternative pathway, is also associated with various r...

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Detalles Bibliográficos
Autores principales: Liu, Maojing, Wang, Yaqin, Wang, Fengmei, Xia, Min, Liu, Ying, Chen, Yuqing, Zhao, Ming‐Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020621/
https://www.ncbi.nlm.nih.gov/pubmed/27113631
http://dx.doi.org/10.1111/jcmm.12872