Trichostatin A, a histone deacetylase inhibitor suppresses NADPH Oxidase 4‐Derived Redox Signalling and Angiogenesis

Histone deacetylase (HDAC) inhibitors are known to suppress abnormal development of blood vessels. Angiogenic activity in endothelial cells depends upon NADPH oxidase 4 (Nox4)‐dependent redox signalling. We set out to study whether the HDAC inhibitor trichostatin A (TSA) affects Nox4 expression and...

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Detalles Bibliográficos
Autores principales: Hakami, Nora Y., Dusting, Gregory J., Peshavariya, Hitesh M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020625/
https://www.ncbi.nlm.nih.gov/pubmed/27297729
http://dx.doi.org/10.1111/jcmm.12885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020625/
https://www.ncbi.nlm.nih.gov/pubmed/27297729
http://dx.doi.org/10.1111/jcmm.12885

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