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Heat shock protein 70 and AMP‐activated protein kinase contribute to 17‐DMAG‐dependent protection against heat stroke

Heat shock protein 70 (Hsp70) preconditioning induces thermotolerance, and adenosine monophosphate (AMP)‐activated protein kinase (AMPK) plays a role in the process of autophagy. Here, we investigated whether 17‐dimethylaminoethylamino‐17‐demethoxy‐geldanamycin (17‐DMAG) protected against heat strok...

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Detalles Bibliográficos
Autores principales: Tsai, Yung‐Chieh, Lam, Kwok‐Keung, Peng, Yi‐Jen, Lee, Yen‐Mei, Yang, Chung‐Yu, Tsai, Yi‐Ju, Yen, Mao‐Hsiung, Cheng, Pao‐Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020632/
https://www.ncbi.nlm.nih.gov/pubmed/27241357
http://dx.doi.org/10.1111/jcmm.12881