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Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases
The conversion of peptides or proteins from their soluble native states into intractable amyloid deposits is associated with a wide range of human disorders. Misfolded protein oligomers formed during the process of aggregation have been identified as the primary pathogenic agents in many such condit...
Autores principales: | Evangelisti, Elisa, Cascella, Roberta, Becatti, Matteo, Marrazza, Giovanna, Dobson, Christopher M., Chiti, Fabrizio, Stefani, Massimo, Cecchi, Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020652/ https://www.ncbi.nlm.nih.gov/pubmed/27619987 http://dx.doi.org/10.1038/srep32721 |
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