Crocetin exploits p53-induced death domain (PIDD) and FAS-associated death domain (FADD) proteins to induce apoptosis in colorectal cancer

Tumor suppressor p53 preserves the genomic integrity by restricting anomaly at the gene level. The hotspots for mutation in half of all colon cancers reside in p53. Hence, in a p53-mutated cellular milieu targeting cancer cells may be achievable by targeting the paralogue(s) of p53. Here we have sho...

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Detalles Bibliográficos
Autores principales: Ray, Pallab, Guha, Deblina, Chakraborty, Juni, Banerjee, Shuvomoy, Adhikary, Arghya, Chakraborty, Samik, Das, Tanya, Sa, Gaurisankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020693/
https://www.ncbi.nlm.nih.gov/pubmed/27622714
http://dx.doi.org/10.1038/srep32979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020693/
https://www.ncbi.nlm.nih.gov/pubmed/27622714
http://dx.doi.org/10.1038/srep32979

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