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No synergism between bis(propyl)-cognitin and rasagiline on protecting dopaminergic neurons in Parkinson's disease mice

Rasagiline, a monoamine oxidase-B inhibitor, and bis(propyl)-cognitin (B3C), a novel dimer are reported to be neuroprotective. Herein, the synergistical neuroprotection produced by rasagiline and B3C was investigated in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mice of Parkinsonism...

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Detalles Bibliográficos
Autores principales: Zheng, Cheng-you, Guo, Bao-jian, Cai, Wei, Cui, Wei, Mak, Shing-hung, Wang, Yu-qiang, Lee, Simon Ming-yuen, Han, Yi-fan, Zhang, Zai-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020835/
https://www.ncbi.nlm.nih.gov/pubmed/27651784
http://dx.doi.org/10.4103/1673-5374.189201