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Nek2 siRNA therapy using a portal venous port–catheter system for liver metastasis in pancreatic cancer

Nek2 (NIMA‐related kinase 2) is a serine‐threonine kinase and human homolog of the mitotic regulator NIMA of Aspergillus nidulan. We reported the efficiency of Nek2 siRNA in several cancer xenograft models using cholangiocarcinoma, breast cancer and colorectal cancer. Pancreatic cancer is difficult...

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Detalles Bibliográficos
Autores principales: Kokuryo, Toshio, Hibino, Shigeru, Suzuki, Kazushi, Watanabe, Katsutaka, Yokoyama, Yukihiro, Nagino, Masato, Senga, Takeshi, Hamaguchi, Michinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021025/
https://www.ncbi.nlm.nih.gov/pubmed/27316377
http://dx.doi.org/10.1111/cas.12993