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Nek2 siRNA therapy using a portal venous port–catheter system for liver metastasis in pancreatic cancer
Nek2 (NIMA‐related kinase 2) is a serine‐threonine kinase and human homolog of the mitotic regulator NIMA of Aspergillus nidulan. We reported the efficiency of Nek2 siRNA in several cancer xenograft models using cholangiocarcinoma, breast cancer and colorectal cancer. Pancreatic cancer is difficult...
Autores principales: | Kokuryo, Toshio, Hibino, Shigeru, Suzuki, Kazushi, Watanabe, Katsutaka, Yokoyama, Yukihiro, Nagino, Masato, Senga, Takeshi, Hamaguchi, Michinari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021025/ https://www.ncbi.nlm.nih.gov/pubmed/27316377 http://dx.doi.org/10.1111/cas.12993 |
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