Nontoxic concentration of DNA‐PK inhibitor NU7441 radio‐sensitizes lung tumor cells with little effect on double strand break repair

High‐linear energy transfer (LET) heavy ions have been increasingly employed as a useful alternative to conventional photon radiotherapy. As recent studies suggested that high LET radiation mainly affects the nonhomologous end‐joining (NHEJ) pathway of DNA double strand break (DSB) repair, we furthe...

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Detalles Bibliográficos
Autores principales: Sunada, Shigeaki, Kanai, Hideki, Lee, Younghyun, Yasuda, Takeshi, Hirakawa, Hirokazu, Liu, Cuihua, Fujimori, Akira, Uesaka, Mitsuru, Okayasu, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021029/
https://www.ncbi.nlm.nih.gov/pubmed/27341700
http://dx.doi.org/10.1111/cas.12998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021029/
https://www.ncbi.nlm.nih.gov/pubmed/27341700
http://dx.doi.org/10.1111/cas.12998

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