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Histone demethylase LSD1 controls the phenotypic plasticity of cancer cells

Epigenetic mechanisms underlie the phenotypic plasticity of cells, while aberrant epigenetic regulation through genetic mutations and/or misregulated expression of epigenetic factors leads to aberrant cell fate determination, which provides a foundation for oncogenic transformation. Lysine‐specific...

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Detalles Bibliográficos
Autores principales: Hino, Shinjiro, Kohrogi, Kensaku, Nakao, Mitsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021031/
https://www.ncbi.nlm.nih.gov/pubmed/27375009
http://dx.doi.org/10.1111/cas.13004