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Antitumor effect of novel anti‐podoplanin antibody NZ‐12 against malignant pleural mesothelioma in an orthotopic xenograft model

Podoplanin (aggrus) is highly expressed in several types of cancers, including malignant pleural mesothelioma (MPM). Previously, we developed a rat anti‐human podoplanin mAb, NZ‐1, and a rat–human chimeric anti‐human podoplanin antibody, NZ‐8, derived from NZ‐1, which induced antibody‐dependent cell...

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Detalles Bibliográficos
Autores principales: Abe, Shinji, Kaneko, Mika Kato, Tsuchihashi, Yuki, Izumi, Toshihiro, Ogasawara, Satoshi, Okada, Naoto, Sato, Chiemi, Tobiume, Makoto, Otsuka, Kenji, Miyamoto, Licht, Tsuchiya, Koichiro, Kawazoe, Kazuyoshi, Kato, Yukinari, Nishioka, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021042/
https://www.ncbi.nlm.nih.gov/pubmed/27294401
http://dx.doi.org/10.1111/cas.12985