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Sunitinib: the antiangiogenic effects and beyond

As a multitargeted kinase inhibitor, sunitinib has carved its way into demonstrating itself as a most effective tyrosine kinase inhibitor in the treatment of metastatic renal cell carcinoma. Mechanistically, sunitinib inhibits multiple receptor tyrosine kinases, especially those involved in angiogen...

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Detalles Bibliográficos
Autores principales: Hao, Zhonglin, Sadek, Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021055/
https://www.ncbi.nlm.nih.gov/pubmed/27660467
http://dx.doi.org/10.2147/OTT.S112242