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PEX2 is the E3 ubiquitin ligase required for pexophagy during starvation

Peroxisomes are metabolic organelles necessary for anabolic and catabolic lipid reactions whose numbers are highly dynamic based on the metabolic need of the cells. One mechanism to regulate peroxisome numbers is through an autophagic process called pexophagy. In mammalian cells, ubiquitination of p...

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Detalles Bibliográficos
Autores principales: Sargent, Graeme, van Zutphen, Tim, Shatseva, Tatiana, Zhang, Ling, Di Giovanni, Valeria, Bandsma, Robert, Kim, Peter Kijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021090/
https://www.ncbi.nlm.nih.gov/pubmed/27597759
http://dx.doi.org/10.1083/jcb.201511034