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Beyond the SNARE: Munc18-1 chaperones α-synuclein
Early infantile epileptic encephalopathy (EIEE)–associated mutations in MUNC18-1 cause Munc18-1 misfolding and cellular aggregation. In this issue, Chai et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201512016) find that Munc18-1 is a molecular chaperone for α-synuclein and that aggregate...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021099/ https://www.ncbi.nlm.nih.gov/pubmed/27597757 http://dx.doi.org/10.1083/jcb.201608060 |