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Detecting Cooperativity between Transcription Factors Based on Functional Coherence and Similarity of Their Target Gene Sets
In eukaryotic cells, transcriptional regulation of gene expression is usually achieved by cooperative transcription factors (TFs). Therefore, knowing cooperative TFs is the first step toward uncovering the molecular mechanisms of gene expression regulation. Many algorithms based on different rationa...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021274/ https://www.ncbi.nlm.nih.gov/pubmed/27623007 http://dx.doi.org/10.1371/journal.pone.0162931 |