Leptospira Immunoglobulin-Like Protein B (LigB) Binds to Both the C-Terminal 23 Amino Acids of Fibrinogen αC Domain and Factor XIII: Insight into the Mechanism of LigB-Mediated Blockage of Fibrinogen α Chain Cross-Linking

The coagulation system provides a primitive but effective defense against hemorrhage. Soluble fibrinogen (Fg) monomers, composed of α, β and γ chains, are recruited to provide structural support for the formation of a hemostatic plug. Fg binds to platelets and is processed into a cross-linked fibrin...

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Detalles Bibliográficos
Autores principales: Hsieh, Ching-Lin, Chang, Eric, Tseng, Andrew, Ptak, Christopher, Wu, Li-Chen, Su, Chun-Li, McDonough, Sean P., Lin, Yi-Pin, Chang, Yung-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021285/
https://www.ncbi.nlm.nih.gov/pubmed/27622634
http://dx.doi.org/10.1371/journal.pntd.0004974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021285/
https://www.ncbi.nlm.nih.gov/pubmed/27622634
http://dx.doi.org/10.1371/journal.pntd.0004974

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