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The Arginine/Lysine-Rich Element within the DNA-Binding Domain Is Essential for Nuclear Localization and Function of the Intracellular Pathogen Resistance 1

The mouse intracellular pathogen resistance 1 (Ipr1) gene plays important roles in mediating host immunity and previous work showed that it enhances macrophage apoptosis upon mycobacterium infection. However, to date, little is known about the regulation pattern of Ipr1 action. Recent studies have i...

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Detalles Bibliográficos
Autores principales: Yao, Kezhen, Wu, Yongyan, Chen, Qi, Zhang, Zihan, Chen, Xin, Zhang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021326/
https://www.ncbi.nlm.nih.gov/pubmed/27622275
http://dx.doi.org/10.1371/journal.pone.0162832