A Novel High-Throughput 3D Screening System for EMT Inhibitors: A Pilot Screening Discovered the EMT Inhibitory Activity of CDK2 Inhibitor SU9516

Epithelial-mesenchymal transition (EMT) is a crucial pathological event in cancer, particularly in tumor cell budding and metastasis. Therefore, control of EMT can represent a novel therapeutic strategy in cancer. Here, we introduce an innovative three-dimensional (3D) high-throughput screening (HTS...

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Detalles Bibliográficos
Autores principales: Arai, Kazuya, Eguchi, Takanori, Rahman, M. Mamunur, Sakamoto, Ruriko, Masuda, Norio, Nakatsura, Tetsuya, Calderwood, Stuart K., Kozaki, Ken-ichi, Itoh, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021355/
https://www.ncbi.nlm.nih.gov/pubmed/27622654
http://dx.doi.org/10.1371/journal.pone.0162394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021355/
https://www.ncbi.nlm.nih.gov/pubmed/27622654
http://dx.doi.org/10.1371/journal.pone.0162394

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