Cargando…

SPARC Regulates Transforming Growth Factor Beta Induced (TGFBI) Extracellular Matrix Deposition and Paclitaxel Response in Ovarian Cancer Cells

TGFBI has been shown to sensitize ovarian cancer cells to the cytotoxic effects of paclitaxel via an integrin receptor-mediated mechanism that modulates microtubule stability. Herein, we determine that TGFBI localizes within organized fibrillar structures in mesothelial-derived ECM. We determined th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tumbarello, David A., Andrews, Melissa R., Brenton, James D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021370/ https://www.ncbi.nlm.nih.gov/pubmed/27622658 http://dx.doi.org/10.1371/journal.pone.0162698

Ejemplares similares

ß3 integrin modulates transforming growth factor beta induced (TGFBI) function and paclitaxel response in ovarian cancer cells
por: Tumbarello, David A, et al.
Publicado: (2012)

The Extracellular Matrix Protein TGFBI Induces Microtubule Stabilization and Sensitizes Ovarian Cancers to Paclitaxel
por: Ahmed, Ahmed Ashour, et al.
Publicado: (2007)

TGFBI promoter hypermethylation correlating with paclitaxel chemoresistance in ovarian cancer
por: Wang, Ning, et al.
Publicado: (2012)

Transforming Growth Factor-Beta-Induced Protein (TGFBI)/(βig-H3): A Matrix Protein with Dual Functions in Ovarian Cancer
por: Ween, Miranda P., et al.
Publicado: (2012)

The role of SPARC in extracellular matrix assembly
por: Bradshaw, Amy D.
Publicado: (2009)

Genotypic Homogeneity in Distinctive Transforming Growth Factor-Beta Induced (TGFBI) Protein Phenotypes
por: Han, Sang Beom, et al.
Publicado: (2021)

Tumor-associated macrophages promote ovarian cancer cell migration by secreting transforming growth factor beta induced (TGFBI) and tenascin C
por: Steitz, Anna Mary, et al.
Publicado: (2020)

Endothelial angiogenic activity and adipose angiogenesis is controlled by extracellular matrix protein TGFBI
por: Lee, Seul Gi, et al.
Publicado: (2021)

TGFBI is involved in the formation of polyploid cancer cells and the response to paclitaxel
por: Shang, Xiaobin, et al.
Publicado: (2021)

Comprehensively investigating the expression levels and the prognostic role of transforming growth factor beta-induced (TGFBI) in glioblastoma multiforme
por: Yin, Jun, et al.
Publicado: (2020)

TGFBI Production by Macrophages Contributes to an Immunosuppressive Microenvironment in Ovarian Cancer
por: Lecker, Laura S.M., et al.
Publicado: (2021)

Age and SPARC Change the Extracellular Matrix Composition of the Left Ventricle
por: de Castro Brás, Lisandra E., et al.
Publicado: (2014)

Implication of SPARC in the modulation of the extracellular matrix and mitochondrial function in muscle cells
por: Melouane, Aicha, et al.
Publicado: (2018)

Investigation of TGFBI (Transforming growth factor beta-induced) Gene Mutations in Families with Granular Corneal Dystrophy Type 1 in the Konya Region
por: Malkondu, Fatma, et al.
Publicado: (2020)

Evidence against a blood derived origin for transforming growth factor beta induced protein in corneal disorders caused by mutations in the TGFBI gene
por: Karring, Henrik, et al.
Publicado: (2007)

Identification of transforming growth factor beta induced (TGFBI) as an immune-related prognostic factor in clear cell renal cell carcinoma (ccRCC)
por: Du, Guo-Wei, et al.
Publicado: (2020)

Association of Differentially Altered Liver Fibrosis with Deposition of TGFBi in Stabilin-Deficient Mice
por: Krzistetzko, Jessica, et al.
Publicado: (2023)

Pharmaceutical modulation of the proteolytic profile of Transforming Growth Factor Beta induced protein (TGFBIp) offers a new avenue for treatment of TGFBI-corneal dystrophy
por: Venkatraman, Anandalakshmi, et al.
Publicado: (2020)

The Effects of Age and the Expression of SPARC on Extracellular Matrix Production by Cardiac Fibroblasts in 3-D Cultures
por: Trombetta-eSilva, Jessica, et al.
Publicado: (2013)

Dual role for the latent transforming growth factor-beta binding protein in storage of latent TGF-beta in the extracellular matrix and as a structural matrix protein
Publicado: (1995)

SPARC Inhibits Metabolic Plasticity in Ovarian Cancer
por: Naczki, Christine, et al.
Publicado: (2018)

Relationship of transforming growth factor beta 1 to extracellular matrix and stromal infiltrates in invasive breast carcinoma.
por: Walker, R. A., et al.
Publicado: (1994)

Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein
Publicado: (1994)

Epithelium-dependent extracellular matrix synthesis in transforming growth factor-beta 1-growth-inhibited mouse mammary gland
Publicado: (1990)

SPARC independent drug delivery and antitumour effects of nab-paclitaxel in genetically engineered mice
por: Neesse, Albrecht, et al.
Publicado: (2014)

A pathogenic variant in the transforming growth factor beta I (TGFBI) in four Iranian extended families segregating granular corneal dystrophy type II: A literature review
por: Mohammadi, Aliasgar, et al.
Publicado: (2020)

Expression and significance of transforming growth factor-β1 in epithelial ovarian cancer and its extracellular matrix
por: CHEN, KEMING, et al.
Publicado: (2014)

Phenotypic modulation of endothelial cells by transforming growth factor-beta depends upon the composition and organization of the extracellular matrix
Publicado: (1988)

SPARC coordinates extracellular matrix remodeling and efficient recruitment to and migration of antigen-specific T cells in the brain following infection
por: McGovern, Kathryn E., et al.
Publicado: (2021)

Control of cytokine-driven eosinophil migratory behavior by TGF-beta-induced protein (TGFBI) and periostin
por: Barretto, Karina T., et al.
Publicado: (2018)

Spatio-temporal expression profile of matrix metalloproteinase (Mmp) modulators Reck and Sparc during the rat ovarian dynamics
por: Levin, Gabriel, et al.
Publicado: (2018)

IGF-1 regulates the growth of fibroblasts and extracellular matrix deposition in pelvic organ prolapse
por: Yin, Yitong, et al.
Publicado: (2020)

Characterization of extracellular matrix deposited by segmental trabecular meshwork cells
por: Raghunathan, VijayKrishna, et al.
Publicado: (2023)

Extracellular SPARC increases cardiomyocyte contraction during health and disease
por: Deckx, Sophie, et al.
Publicado: (2019)

Tetrahydrocurcumin Chemosensitizes Breast Cancer to Albumin-Bound Paclitaxel by Enhancing SPARC Expression through Demethylation
por: Qiu, Dongjie, et al.
Publicado: (2022)

SPARC Is Highly Expressed in Young Skin and Promotes Extracellular Matrix Integrity in Fibroblasts via the TGF-β Signaling Pathway
por: Ham, Seung Min, et al.
Publicado: (2023)

Targeted therapy for the post-operative conjunctiva: SPARC silencing reduces collagen deposition
por: Seet, Li Fong, et al.
Publicado: (2018)

SPARC Is a Key Regulator of Proliferation, Apoptosis and Invasion in Human Ovarian Cancer
por: Chen, Jie, et al.
Publicado: (2012)

Enhanced production and extracellular deposition of the endothelial- type plasminogen activator inhibitor in cultured human lung fibroblasts by transforming growth factor-beta
Publicado: (1986)

SPARC's Initiative
por: Alison Buckholtz
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_v7ouao0qh496upqjrabr1q7n76