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Nonhuman TRIM5 Variants Enhance Recognition of HIV-1-Infected Cells by CD8(+) T Cells

Tripartite motif-containing protein 5 (TRIM5) restricts human immunodeficiency virus type 1 (HIV-1) in a species-specific manner by uncoating viral particles while activating early innate responses. Although the contribution of TRIM5 proteins to cellular immunity has not yet been studied, their inte...

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Detalles Bibliográficos
Autores principales: Jimenez-Moyano, Esther, Ruiz, Alba, Kløverpris, Henrik N., Rodriguez-Plata, Maria T., Peña, Ruth, Blondeau, Caroline, Selwood, David L., Izquierdo-Useros, Nuria, Moris, Arnaud, Clotet, Bonaventura, Goulder, Philip, Towers, Greg J., Prado, Julia G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021395/
https://www.ncbi.nlm.nih.gov/pubmed/27440884
http://dx.doi.org/10.1128/JVI.00819-16