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Deep Sequencing of Distinct Preparations of the Live Attenuated Varicella-Zoster Virus Vaccine Reveals a Conserved Core of Attenuating Single-Nucleotide Polymorphisms

The continued success of the live attenuated varicella-zoster virus vaccine in preventing varicella-zoster and herpes zoster is well documented, as are many of the mutations that contribute to the attenuation of the vOka virus for replication in skin. At least three different preparations of vOka ar...

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Detalles Bibliográficos
Autores principales: Depledge, Daniel P., Yamanishi, Koichi, Gomi, Yasuyuki, Gershon, Anne A., Breuer, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021409/
https://www.ncbi.nlm.nih.gov/pubmed/27440875
http://dx.doi.org/10.1128/JVI.00998-16