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Complementary Effects of Interleukin-15 and Alpha Interferon Induce Immunity in Hepatitis B Virus Transgenic Mice

In chronic hepatitis B (CHB), failure to control hepatitis B virus (HBV) is associated with T cell dysfunction. HBV transgenic mice mirror many features of the human disease, including T cell unresponsiveness, and thus represent an appropriate model in which to test novel therapeutic strategies. To...

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Detalles Bibliográficos
Autores principales: Di Scala, Marianna, Otano, Itziar, Gil-Fariña, Irene, Vanrell, Lucia, Hommel, Mirja, Olagüe, Cristina, Vales, Africa, Galarraga, Miguel, Guembe, Laura, Ortiz de Solorzano, Carlos, Ghosh, Indrajit, Maini, Mala K., Prieto, Jesús, González-Aseguinolaza, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021417/
https://www.ncbi.nlm.nih.gov/pubmed/27440883
http://dx.doi.org/10.1128/JVI.01030-16