Osteopontin Promotes Expression of Matrix Metalloproteinase 13 through NF-κB Signaling in Osteoarthritis

Osteopontin (OPN) is associated with the severity and progression of osteoarthritis (OA); however, the mechanism of OPN in the pathogenesis of OA is unknown. In this study, we found that OA patients had higher abundance of OPN and matrix metalloproteinase 13 (MMP13). In chondrocytes, we showed that...

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Detalles Bibliográficos
Autores principales: Li, Yusheng, Jiang, Wei, Wang, Hua, Deng, Zhenhan, Zeng, Chao, Tu, Min, Li, Liangjun, Xiao, Wenfeng, Gao, Shuguang, Luo, Wei, Lei, Guanghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021466/
https://www.ncbi.nlm.nih.gov/pubmed/27656654
http://dx.doi.org/10.1155/2016/6345656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021466/
https://www.ncbi.nlm.nih.gov/pubmed/27656654
http://dx.doi.org/10.1155/2016/6345656

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