Cargando…

Osteopontin Promotes Expression of Matrix Metalloproteinase 13 through NF-κB Signaling in Osteoarthritis

Osteopontin (OPN) is associated with the severity and progression of osteoarthritis (OA); however, the mechanism of OPN in the pathogenesis of OA is unknown. In this study, we found that OA patients had higher abundance of OPN and matrix metalloproteinase 13 (MMP13). In chondrocytes, we showed that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yusheng, Jiang, Wei, Wang, Hua, Deng, Zhenhan, Zeng, Chao, Tu, Min, Li, Liangjun, Xiao, Wenfeng, Gao, Shuguang, Luo, Wei, Lei, Guanghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021466/ https://www.ncbi.nlm.nih.gov/pubmed/27656654 http://dx.doi.org/10.1155/2016/6345656

Ejemplares similares

MicroRNA-127-5p regulates osteopontin expression and osteopontin-mediated proliferation of human chondrocytes
por: Tu, Min, et al.
Publicado: (2016)

The Expression of Osteopontin and Wnt5a in Articular Cartilage of Patients with Knee Osteoarthritis and Its Correlation with Disease Severity
por: Li, Yusheng, et al.
Publicado: (2016)

Diet-Intestinal Microbiota Axis in Osteoarthritis: A Possible Role
por: Li, Yusheng, et al.
Publicado: (2016)

Matrix metalloproteinase-13, NF-κB p65 and interleukin-1β are associated with the severity of knee osteoarthritis
por: Zhao, Qing-Hua, et al.
Publicado: (2020)

The expression of SIRT1 in articular cartilage of patients with knee osteoarthritis and its correlation with disease severity
por: Li, Yusheng, et al.
Publicado: (2016)

Potential Value of Matrix Metalloproteinase-13 as a Biomarker for Osteoarthritis
por: Xin, Xing, et al.
Publicado: (2021)

Costunolide inhibits matrix metalloproteinases expression and osteoarthritis via the NF-κB and Wnt/β-catenin signaling pathways
por: He, Yuzhe, et al.
Publicado: (2019)

The role of sirtuin 1 and its activator, resveratrol in osteoarthritis
por: Deng, Zhenhan, et al.
Publicado: (2019)

Roles of osteopontin and matrix metalloproteinase-7 in occurrence, progression, and prognosis of nonsmall cell lung cancer
por: Sun, Ying, et al.
Publicado: (2015)

The involvement of osteopontin and matrix metalloproteinase- 9 in the migration of endometrial epithelial cells in patients with endometriosis
por: Yang, Mei, et al.
Publicado: (2015)

p38MAPK Signaling Pathway in Osteoarthritis: Pathological and Therapeutic Aspects
por: Li, Zongchao, et al.
Publicado: (2022)

Relationship Between Magnetic Resonance T2-Mapping and Matrix Metalloproteinase 1,3 in Knee Osteoarthritis
por: Shi, Lei, et al.
Publicado: (2020)

Quercetin prevent proteoglycan destruction by inhibits matrix metalloproteinase-9, matrix metalloproteinase-13, a disintegrin and metalloproteinase with thrombospondin motifs-5 expressions on osteoarthritis model rats
por: Permatasari, Dian Agustina, et al.
Publicado: (2019)

MicroRNA-200b acts as a tumor suppressor in osteosarcoma via targeting ZEB1
por: Li, Yusheng, et al.
Publicado: (2016)

NF-κB and Matrix-Dependent Regulation of Osteopontin Promoter Activity in Allylamine-Activated Vascular Smooth Muscle Cells
por: Williams, E. Spencer, et al.
Publicado: (2012)

Expression of osteopontin, matrix metalloproteinase-2 and -9 proteins in vascular instability in brain arteriovenous malformation
por: Anbarasen, Lalita, et al.
Publicado: (2019)

Exercise-induced responses in matrix metalloproteinases and osteopontin are not moderated by exercise format in males with overweight or obesity
por: Raman, Aaron, et al.
Publicado: (2023)

Allele-Specific Regulation of Matrix Metalloproteinase-3 Gene by Transcription Factor NFκB
por: Souslova, Veronika, et al.
Publicado: (2010)

Clusterin Silencing in Prostate Cancer Induces Matrix Metalloproteinases by an NF-κB-Dependent Mechanism
por: Bonacini, Martina, et al.
Publicado: (2019)

Correction to: Relationship Between Magnetic Resonance T2-Mapping and Matrix Metalloproteinase 1,3 in Knee Osteoarthritis
por: Shi, Lei, et al.
Publicado: (2021)

Tumor-derived Matrix Metalloproteinase-13 (MMP-13) correlates with poor prognoses of invasive breast cancer
por: Zhang, Bin, et al.
Publicado: (2008)

The Role of Matrix Metalloproteinase 13 and Vitamin D in Osteoarthritis: A Hospital-Based Observational Study
por: Kumar, Purushottam, et al.
Publicado: (2023)

Inhibition of Cellular Adhesion by Immunological Targeting of Osteopontin Neoepitopes Generated through Matrix Metalloproteinase and Thrombin Cleavage
por: Jürets, Alexander, et al.
Publicado: (2016)

Interleukin-12-mediated expression of matrix metalloproteinases in human periodontal ligament fibroblasts involves in NF-κB activation
por: Miao, Li, et al.
Publicado: (2017)

Curcumin Inhibits Proliferation of Synovial Cells by Downregulating Expression of Matrix Metalloproteinase‐3 in Osteoarthritis
por: Zeng, Jian‐jun, et al.
Publicado: (2018)

Downregulation of microRNA-9 increases matrix metalloproteinase-13 expression levels and facilitates osteoarthritis onset
por: Zhang, Hongxin, et al.
Publicado: (2018)

Follistatin‐like protein 1 (FSTL1) promotes chondrocyte expression of matrix metalloproteinase and inflammatory factors via the NF‐κB pathway
por: Hu, Peng‐Fei, et al.
Publicado: (2019)

Osteopontin, a bridge links osteoarthritis and osteoporosis
por: Bai, Rui-Jun, et al.
Publicado: (2022)

Matrix metalloproteinase‐13 unlucky for the forming thrombus
por: Montague, Samantha J., et al.
Publicado: (2018)

Osteopontin May Improve Postinjury Muscle Repair Via Matrix Metalloproteinases And tgf-β Activation in Regular Exercise
por: Wang, Yuchong, et al.
Publicado: (2023)

Haloperidol Abrogates Matrix Metalloproteinase-9 Expression by Inhibition of NF-κB Activation in Stimulated Human Monocytic Cells
por: Lee, Yueh-Lun, et al.
Publicado: (2018)

Two-stage total hip arthroplasty for patients with advanced active tuberculosis of the hip
por: Li, Liangjun, et al.
Publicado: (2016)

Osteopontin (OPN) alleviates the progression of osteoarthritis by promoting the anabolism of chondrocytes
por: Luo, Wei, et al.
Publicado: (2022)

Regulation and Function of Matrix Metalloproteinase-13 in Cancer Progression and Metastasis
por: Li, Shun, et al.
Publicado: (2022)

Acacetin Suppresses IL-1β-Induced Expression of Matrix Metalloproteinases in Chondrocytes and Protects against Osteoarthritis in a Mouse Model by Inhibiting NF-κB Signaling Pathways
por: Chen, Jian, et al.
Publicado: (2020)

Association between matrix metalloproteinase-1 (MMP-1) protein level and the risk of rheumatoid arthritis and osteoarthritis: a meta-analysis
por: Wang, Maopeng, et al.
Publicado: (2020)

Tea polyphenols inhibit the activation of NF-κB and the secretion of cytokines and matrix metalloproteinases by macrophages stimulated with Fusobacterium nucleatum
por: Lagha, Amel Ben, et al.
Publicado: (2016)

Expression of Matrix Metalloproteinase-2 and -13 and Tissue Inhibitor of Metalloproteinase-4 in Varicose Veins
por: Chang, Jee Won, et al.
Publicado: (2011)

Pravastatin Reduces Matrix Metalloproteinases Expression and Promotes Cholesterol Efflux in Osteoarthritis Chondrocytes
por: Wu, Yunpeng, et al.
Publicado: (2022)

Effect of Posterior Cruciate Ligament Rupture on Biomechanical and Histological Features of Lateral Femoral Condyle
por: Deng, Zhenhan, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_hohpebg7f3ko05gb21g5lhugt7