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Exendin-4 Promotes Survival of Mouse Pancreatic β-Cell Line in Lipotoxic Conditions, through the Extracellular Signal-Related Kinase 1/2 Pathway

Type 2 diabetes is a heterogeneous disorder that develops as a result of relatively inappropriate insulin secretion and insulin resistance. Increased levels of free fatty acids (FFAs) are one of the important factors for the pathogenesis of type 2 diabetes and contribute to defective β-cell prolifer...

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Detalles Bibliográficos
Autores principales: Gu, Jianqiu, Wei, Qian, Zheng, Hongzhi, Meng, Xin, Zhang, Jin, Wang, Difei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021481/
https://www.ncbi.nlm.nih.gov/pubmed/27656657
http://dx.doi.org/10.1155/2016/5294025