Microbially produced glucagon-like peptide 1 improves glucose tolerance in mice

OBJECTIVE: The enteroendocrine hormone glucagon-like peptide 1 (GLP-1) is an attractive anti-diabetic therapy. Here, we generated a recombinant Lactococcus lactis strain genetically modified to produce GLP-1 and investigated its ability to improve glucose tolerance in mice on chow or high-fat diet (...

Descripción completa

Detalles Bibliográficos
Autores principales: Arora, Tulika, Wegmann, Udo, Bobhate, Anup, Lee, Ying Shiuan, Greiner, Thomas U., Drucker, Daniel J., Narbad, Arjan, Bäckhed, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021674/
https://www.ncbi.nlm.nih.gov/pubmed/27656410
http://dx.doi.org/10.1016/j.molmet.2016.06.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021674/
https://www.ncbi.nlm.nih.gov/pubmed/27656410
http://dx.doi.org/10.1016/j.molmet.2016.06.006

Ejemplares similares