Cargando…

Microbially produced glucagon-like peptide 1 improves glucose tolerance in mice

OBJECTIVE: The enteroendocrine hormone glucagon-like peptide 1 (GLP-1) is an attractive anti-diabetic therapy. Here, we generated a recombinant Lactococcus lactis strain genetically modified to produce GLP-1 and investigated its ability to improve glucose tolerance in mice on chow or high-fat diet (...

Descripción completa

Detalles Bibliográficos
Autores principales:	Arora, Tulika, Wegmann, Udo, Bobhate, Anup, Lee, Ying Shiuan, Greiner, Thomas U., Drucker, Daniel J., Narbad, Arjan, Bäckhed, Fredrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021674/ https://www.ncbi.nlm.nih.gov/pubmed/27656410 http://dx.doi.org/10.1016/j.molmet.2016.06.006

Ejemplares similares

Insulin-like peptide 5 is a microbially regulated peptide that promotes hepatic glucose production
por: Lee, Ying Shiuan, et al.
Publicado: (2016)

Microbial regulation of GLP-1 and L-cell biology
por: Greiner, Thomas U., et al.
Publicado: (2016)

A short-oligonucleotide microarray that allows improved detection of gastrointestinal tract microbial communities
por: Harrington, Carl R, et al.
Publicado: (2008)

Complete Genome Sequence of Desulfovibrio piger FI11049
por: Wegmann, Udo, et al.
Publicado: (2017)

Expression and delivery of an endolysin to combat Clostridium perfringens
por: Gervasi, Teresa, et al.
Publicado: (2013)

Establishment of a Refined Oral Glucose Tolerance Test in Pigs, and Assessment of Insulin, Glucagon and Glucagon-Like Peptide-1 Responses
por: Manell, Elin, et al.
Publicado: (2016)

Improvement of Glucose Tolerance by Food Factors Having Glucagon-Like Peptide-1 Releasing Activity
por: Hira, Tohru, et al.
Publicado: (2021)

Modelling the effects of glucagon during glucose tolerance testing
por: Kelly, Ross A., et al.
Publicado: (2019)

Role of Central Nervous System Glucagon-Like Peptide-1 Receptors in Enteric Glucose Sensing
por: Knauf, Claude, et al.
Publicado: (2008)

Microbial regulation of the L cell transcriptome
por: Arora, Tulika, et al.
Publicado: (2018)

Impaired Secretion of Total Glucagon-like Peptide-1 in People with Impaired Fasting Glucose Combined Impaired Glucose Tolerance
por: Zhang, Fang, et al.
Publicado: (2012)

Glucagon-like peptide-1 receptor co-agonists for treating metabolic disease
por: Baggio, Laurie L., et al.
Publicado: (2020)

Microbial metabolite p-cresol inhibits gut hormone expression and regulates small intestinal transit in mice
por: Toft, Pernille Baumann, et al.
Publicado: (2023)

Protein Engineering Strategies for Sustained Glucagon-Like Peptide-1 Receptor–Dependent Control of Glucose Homeostasis
por: Picha, Kristen M., et al.
Publicado: (2008)

Complete Genome Sequence of Ochrobactrum haematophilum FI11154, Isolated from Kunu-Zaki, a Nigerian Millet-Based Fermented Food
por: Diaz, Maria, et al.
Publicado: (2018)

Gut-derived lipopolysaccharide augments adipose macrophage accumulation but is not essential for impaired glucose or insulin tolerance in mice
por: Caesar, Robert, et al.
Publicado: (2012)

The Hypothalamic Glucagon-Like Peptide 1 Receptor Is Sufficient but Not Necessary for the Regulation of Energy Balance and Glucose Homeostasis in Mice
por: Burmeister, Melissa A., et al.
Publicado: (2017)

Mathematical Model of Glucagon Kinetics for the Assessment of Insulin-Mediated Glucagon Inhibition During an Oral Glucose Tolerance Test
por: Morettini, Micaela, et al.
Publicado: (2021)

Analysis of gut microbial regulation of host gene expression along the length of the gut and regulation of gut microbial ecology through MyD88
por: Larsson, Erik, et al.
Publicado: (2011)

Pregnancy glucagon-like peptide 1 predicts insulin but not glucose concentrations
por: Jones, Danielle L., et al.
Publicado: (2023)

Delphinidin 3‐rutinoside‐rich blackcurrant extract ameliorates glucose tolerance by increasing the release of glucagon‐like peptide‐1 secretion
por: Tani, Tsubasa, et al.
Publicado: (2017)

Differences in the Central Anorectic Effects of Glucagon-Like Peptide-1 and Exendin-4 in Rats
por: Barrera, Jason G., et al.
Publicado: (2009)

Glucagon-like peptide 1 (GLP-1)
por: Müller, T.D., et al.
Publicado: (2019)

Enteroendocrine-derived glucagon-like peptide-2 controls intestinal amino acid transport
por: Lee, Jennifer, et al.
Publicado: (2017)

Association of glucagon‐like peptide‐1 receptor‐targeted imaging probe with in vivo glucagon‐like peptide‐1 receptor agonist glucose‐lowering effects
por: Murakami, Takaaki, et al.
Publicado: (2020)

Computational Peptide Design Cotargeting Glucagon and Glucagon-like Peptide-1 Receptors
por: Vishnoi, Shubham, et al.
Publicado: (2023)

The gut hormone glucagon-like peptide-1 produced in brain: is this physiologically relevant?
por: Trapp, Stefan, et al.
Publicado: (2013)

Ghrelin and glucagon-like peptide-1 according to body adiposity and glucose homeostasis
por: Lopes, Karynne Grutter, et al.
Publicado: (2023)

Glucagon-Like Peptide-2 Stimulates S-Phase Entry of Intestinal Lgr5+ Stem Cells
por: Chen, Maegan E., et al.
Publicado: (2022)

Glucagon‐like peptide‐1 and glucose‐dependent insulinotropic peptide: effects alone and in combination on insulin secretion and glucose disappearance in mice
por: Pacini, Giovanni, et al.
Publicado: (2017)

Glucose-sensing glucagon-like peptide-1 receptor neurons in the dorsomedial hypothalamus regulate glucose metabolism
por: Huang, Zhaohuan, et al.
Publicado: (2022)

Stability of glucagon-like peptide 1 and glucagon in human plasma
por: Wewer Albrechtsen, Nicolai J, et al.
Publicado: (2015)

Impaired secretion of glucagon-like peptide 1 during oral glucose tolerance test in patients with newly diagnosed type 2 diabetes mellitus
por: Wang, Xiao-Li, et al.
Publicado: (2016)

Arcuate Glucagon-Like Peptide 1 Receptors Regulate Glucose Homeostasis but Not Food Intake
por: Sandoval, Darleen A., et al.
Publicado: (2008)

Mechanisms underlying glucose‐dependent insulinotropic polypeptide and glucagon‐like peptide‐1 secretion
por: Reimann, Frank, et al.
Publicado: (2016)

Carbohydrate‐induced secretion of glucose‐dependent insulinotropic polypeptide and glucagon‐like peptide‐1
por: Seino, Yusuke, et al.
Publicado: (2016)

Spontaneous Mutation Reveals Influence of Exopolysaccharide on Lactobacillus johnsonii Surface Characteristics
por: Horn, Nikki, et al.
Publicado: (2013)

Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test
por: Jonsson, Anna, et al.
Publicado: (2021)

Brain Glucagon-Like Peptide-1 Regulates Arterial Blood Flow, Heart Rate, and Insulin Sensitivity
por: Cabou, Cendrine, et al.
Publicado: (2008)

Glucagon-Like Peptide-1 Receptor Agonist and Glucagon Increase Glucose-Stimulated Insulin Secretion in Beta Cells via Distinct Adenylyl Cyclases
por: Lee, Young-Sun, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_h551b4jdb6jrcds8a8fa2vsfs4