Cholinesterase inhibitors, donepezil and rivastigmine, attenuate spatial memory and cognitive flexibility impairment induced by acute ethanol in the Barnes maze task in rats

Central cholinergic dysfunction contributes to acute spatial memory deficits produced by ethanol administration. Donepezil and rivastigmine elevate acetylcholine levels in the synaptic cleft through the inhibition of cholinesterases—enzymes involved in acetylcholine degradation. The aim of our study...

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Detalles Bibliográficos
Autores principales: Gawel, Kinga, Labuz, Krzysztof, Gibula-Bruzda, Ewa, Jenda, Malgorzata, Marszalek-Grabska, Marta, Filarowska, Joanna, Silberring, Jerzy, Kotlinska, Jolanta H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021718/
https://www.ncbi.nlm.nih.gov/pubmed/27376896
http://dx.doi.org/10.1007/s00210-016-1269-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021718/
https://www.ncbi.nlm.nih.gov/pubmed/27376896
http://dx.doi.org/10.1007/s00210-016-1269-8

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