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The nociceptin/orphanin FQ receptor agonist SR-8993 as a candidate therapeutic for alcohol use disorders: validation in rat models

ABSTRACT: RATIONALE: Alcoholism is a complex disorder in which diverse pathophysiological processes contribute to initiation and progression, resulting in a high degree of heterogeneity among patients. Few pharmacotherapies are presently available, and patient responses to these are variable. The no...

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Detalles Bibliográficos
Autores principales: Aziz, Abdul Maruf Asif, Brothers, Shaun, Sartor, Gregory, Holm, Lovisa, Heilig, Markus, Wahlestedt, Claes, Thorsell, Annika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021736/
https://www.ncbi.nlm.nih.gov/pubmed/27515665
http://dx.doi.org/10.1007/s00213-016-4385-8