Comparison of R-ketamine and rapastinel antidepressant effects in the social defeat stress model of depression

RATIONALE: The N-methyl-d-aspartate (NMDA) receptor antagonists, including R-ketamine and rapastinel (formerly GLYX-13), show rapid antidepressant effects in animal models of depression. OBJECTIVE: We compared the rapid and sustained antidepressant effects of R-ketamine and rapastinel in the social...

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Detalles Bibliográficos
Autores principales: Yang, Bangkun, Zhang, Ji-chun, Han, Mei, Yao, Wei, Yang, Chun, Ren, Qian, Ma, Min, Chen, Qian-Xue, Hashimoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021744/
https://www.ncbi.nlm.nih.gov/pubmed/27488193
http://dx.doi.org/10.1007/s00213-016-4399-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021744/
https://www.ncbi.nlm.nih.gov/pubmed/27488193
http://dx.doi.org/10.1007/s00213-016-4399-2

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