A Simple Method for TPMT and ITPA Genotyping Using Multiplex HRMA for Patients Treated with Thiopurine Drugs

Thiopurine methyltransferase (TPMT) and inosine triphosphatase (ITPA) are crucial enzymes involved in the metabolism of thiopurine drugs: azathioprine and 6-mercaptopurine, used in the treatment of leukemia or inflammatory bowel diseases (IBD). The activity in these enzymes correlates with the genet...

Descripción completa

Detalles Bibliográficos
Autores principales: Skrzypczak-Zielinska, Marzena, Borun, Pawel, Bartkowiak-Kaczmarek, Anna, Zakerska-Banaszak, Oliwia, Walczak, Michal, Dobrowolska, Agnieszka, Kurzawski, Mateusz, Waszak, Malgorzata, Lipinski, Daniel, Plawski, Andrzej, Slomski, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021755/
https://www.ncbi.nlm.nih.gov/pubmed/27307154
http://dx.doi.org/10.1007/s40291-016-0217-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021755/
https://www.ncbi.nlm.nih.gov/pubmed/27307154
http://dx.doi.org/10.1007/s40291-016-0217-0

Ejemplares similares