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Fine resolution mapping of double-strand break sites for human ribosomal DNA units
DNA breakage arises during a variety of biological processes, including transcription, replication and genome rearrangements. In the context of disease, extensive fragmentation of DNA has been described in cancer cells and during early stages of neurodegeneration (Stephens et al., 2011 Stephens et a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021761/ https://www.ncbi.nlm.nih.gov/pubmed/27656414 http://dx.doi.org/10.1016/j.gdata.2016.08.012 |