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Fine resolution mapping of double-strand break sites for human ribosomal DNA units

DNA breakage arises during a variety of biological processes, including transcription, replication and genome rearrangements. In the context of disease, extensive fragmentation of DNA has been described in cancer cells and during early stages of neurodegeneration (Stephens et al., 2011 Stephens et a...

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Detalles Bibliográficos
Autores principales: Pope, Bernard J., Mahmood, Khalid, Jung, Chol-hee, Park, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021761/
https://www.ncbi.nlm.nih.gov/pubmed/27656414
http://dx.doi.org/10.1016/j.gdata.2016.08.012