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Purification of the subcellular compartment in which exogenous antigens undergo endoplasmic reticulum-associated degradation from dendritic cells

Dendritic cells (DCs) are capable of processing and presenting exogenous antigens using MHC class I molecules. This pathway is called antigen cross-presentation and plays an important role in the stimulation of naïve CD8(+) T cells for infectious and tumor immunity. Our previous studies in DC2.4 cel...

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Detalles Bibliográficos
Autores principales: Imai, Jun, Otani, Mayu, Sakai, Takahiro, Hatta, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021789/
https://www.ncbi.nlm.nih.gov/pubmed/27656684
http://dx.doi.org/10.1016/j.heliyon.2016.e00151