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Purification of the subcellular compartment in which exogenous antigens undergo endoplasmic reticulum-associated degradation from dendritic cells
Dendritic cells (DCs) are capable of processing and presenting exogenous antigens using MHC class I molecules. This pathway is called antigen cross-presentation and plays an important role in the stimulation of naïve CD8(+) T cells for infectious and tumor immunity. Our previous studies in DC2.4 cel...
Autores principales: | Imai, Jun, Otani, Mayu, Sakai, Takahiro, Hatta, Shinichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021789/ https://www.ncbi.nlm.nih.gov/pubmed/27656684 http://dx.doi.org/10.1016/j.heliyon.2016.e00151 |
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