Cargando…

RON kinase isoforms demonstrate variable cell motility in normal cells

INTRODUCTION: Aberrant RON (Recepteur d'Origine Nantais) tyrosine kinase activation causes the epithelial cell to evade normal growth pathways, resulting in unregulated cell proliferation, increased cell motility and decreased apoptosis. Wildtype (wt) RON has been shown to play a role in metast...

Descripción completa

Detalles Bibliográficos
Autores principales: Greenbaum, Alissa, Rajput, Ashwani, Wan, Guanghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021793/
https://www.ncbi.nlm.nih.gov/pubmed/27656686
http://dx.doi.org/10.1016/j.heliyon.2016.e00153