Thrombin Cleavage of Plasmodium falciparum Erythrocyte Membrane Protein 1 Inhibits Cytoadherence

Plasmodium falciparum malaria remains one of the most deadly infections worldwide. The pathogenesis of the infection results from the sequestration of infected erythrocytes (IRBC) in vital organs, including the brain, with resulting impairment of blood flow, hypoxia, and lactic acidosis. Sequestrati...

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Detalles Bibliográficos
Autores principales: Gillrie, Mark R., Renaux, Bernard, Russell-Goldman, Eleanor, Avril, Marion, Brazier, Andrew J., Mihara, Koichiro, Di Cera, Enrico, Milner, Danny A., Hollenberg, Morley D., Smith, Joseph D., Ho, May
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021802/
https://www.ncbi.nlm.nih.gov/pubmed/27624125
http://dx.doi.org/10.1128/mBio.01120-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021802/
https://www.ncbi.nlm.nih.gov/pubmed/27624125
http://dx.doi.org/10.1128/mBio.01120-16

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