Tandemly Integrated HPV16 Can Form a Brd4-Dependent Super-Enhancer-Like Element That Drives Transcription of Viral Oncogenes

In cancer cells associated with human papillomavirus (HPV) infections, the viral genome is very often found integrated into the cellular genome. The viral oncogenes E6 and E7 are transcribed from the viral promoter, and integration events that alter transcriptional regulation of this promoter contri...

Descripción completa

Detalles Bibliográficos
Autores principales: Dooley, Katharine E., Warburton, Alix, McBride, Alison A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021809/
https://www.ncbi.nlm.nih.gov/pubmed/27624132
http://dx.doi.org/10.1128/mBio.01446-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021809/
https://www.ncbi.nlm.nih.gov/pubmed/27624132
http://dx.doi.org/10.1128/mBio.01446-16

Ejemplares similares