CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity

The NADPH oxidases are important transmembrane proteins producing reactive oxygen species (ROS). Within the Nox family, different modes of activation can be discriminated. Nox1-3 are dependent on different cytosolic subunits, Nox4 seems to be constitutively active and Nox5 is directly activated by c...

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Detalles Bibliográficos
Autores principales: Prior, Kim-Kristin, Leisegang, Matthias S., Josipovic, Ivana, Löwe, Oliver, Shah, Ajay M., Weissmann, Norbert, Schröder, Katrin, Brandes, Ralf P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021817/
https://www.ncbi.nlm.nih.gov/pubmed/27614387
http://dx.doi.org/10.1016/j.redox.2016.08.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021817/
https://www.ncbi.nlm.nih.gov/pubmed/27614387
http://dx.doi.org/10.1016/j.redox.2016.08.013

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