Thioredoxin Binding Protein-2 Regulates Autophagy of Human Lens Epithelial Cells under Oxidative Stress via Inhibition of Akt Phosphorylation

Oxidative stress plays an essential role in the development of age-related cataract. Thioredoxin binding protein-2 (TBP-2) is a negative regulator of thioredoxin (Trx), which deteriorates cellular antioxidant system. Our study focused on the autophagy-regulating effect of TBP-2 under oxidative stres...

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Detalles Bibliográficos
Autores principales: Zhou, Jiaojie, Yao, Ke, Zhang, Yidong, Chen, Guangdi, Lai, Kairan, Yin, Houfa, Yu, Yibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021881/
https://www.ncbi.nlm.nih.gov/pubmed/27656263
http://dx.doi.org/10.1155/2016/4856431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021881/
https://www.ncbi.nlm.nih.gov/pubmed/27656263
http://dx.doi.org/10.1155/2016/4856431

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