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An Approach for Predicting Essential Genes Using Multiple Homology Mapping and Machine Learning Algorithms

Investigation of essential genes is significant to comprehend the minimal gene sets of cell and discover potential drug targets. In this study, a novel approach based on multiple homology mapping and machine learning method was introduced to predict essential genes. We focused on 25 bacteria which h...

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Detalles Bibliográficos
Autores principales: Hua, Hong-Li, Zhang, Fa-Zhan, Labena, Abraham Alemayehu, Dong, Chuan, Jin, Yan-Ting, Guo, Feng-Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021884/
https://www.ncbi.nlm.nih.gov/pubmed/27660763
http://dx.doi.org/10.1155/2016/7639397